Max Hebditch

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Publications

Hebditch M, Warwicker J
Protein-Sol pKa: prediction of electrostatic frustration, with application to coronaviruses
Bioinformatics 2020


Hebditch M, Kean R and Warwicker J.
Modelling of pH-dependence to develop a strategy for stabilising mAbs at acidic steps in production
Computational and Structrual Biotechnology Journal 2020


Hebditch M and Warwicker J.
Charge and hydrophobicity are key features in sequence-trained machine learning models for predicting the biophysical properties of clinical-stage antibodies
PeerJ 2019


Hebditch M and Warwicker J.
Web-based display of protein surface and pH-dependent properties for assessing the developability of biotherapeutics
Scientific Reports 2019


Hebditch M, Roche A, Curtis R, Warwicker J.
Models for antibody behaviour in hydrophobic interaction chromatography, and in self-association.
Journal of Pharmaceutical Sciences 2018


S√łnderby P, Bukrinski JT, Hebditch M, Peters GHJ, Curtis R, Harris P
Self-Interaction of Human Serum Albumin: A Formulation Perspective.
ACS Omega 2018


Hebditch M, Curtis R, Warwicker J.
Sequence composition predicts immunoglobulin superfamily members that could share the intrinsically disordered properties of antibody CH1 domains.
Scientific Reports 2017


Hebditch M, Carballo-Amador M.A., Charonis S, Curtis R, Warwicker J
Protein-Sol: a web tool for predicting protein solubility from sequence.
Bioinformatics 2017


Corbett D, Hebditch M, Keeling R, Ke P, Ekizoglou Sofia, Pathak J, Van Der Walle C, Uddin S, Baldock C, Avendaño C, Curtis R.
Coarse-Grained Modeling of Antibodies from Small-Angle Scattering Profiles.
Journal Of Physical Chemistry B 2017


Marsden C, Eckersley S, Hebditch M, Kvist A, Milner R, Mitchell D, Warwicker J, Marley A.
The Use of Antibodies in Small-Molecule Drug Discovery.
Journal of biomolecular screening 2014


Williamson M, Hounslow A, Ford J, Fowler K, Hebditch M, Hansen P.
Detection of salt bridges to lysines in solution in barnase.
Chemical Communications 2013